How Cells Resist the Pressure of the Deep Sea

To study the cell membranes of deep-sea animals, the biochemist Itay Budin (center) joined forces with marine biologists Steve Haddock (right) and Jacob Winnikoff (left).

Photographs: From left: Tamrynn Clegg; Geoffroy Tobe; John Lee

“They are looking into an area that, to a large degree, has not been explored,” said Sol Gruner, who researches molecular biophysics at Cornell University; he was consulted for the study but was not a co-author.

Plasmalogen lipids are also found in the human brain, and their role in deep-sea membranes could help explain aspects of cell signaling. More immediately, the research unveils a new way that life has adapted to the most extreme conditions of the deep ocean.

Insane in the Membrane

The cells of all life on Earth are encircled by fatty molecules known as lipids. If you put some lipids in a test tube and add water, they automatically line themselves up…

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