If Bionano’s (BNGO) optical genome mapping (OGM) system Saphyr is to gain mainstream adoption, it has to show its performance improves on standard of care (SOC) methods. So far, it appears to be doing just that.
There have been several publications so far demonstrating its usefulness and on Friday, the company announced the first publication showing OGM’s role as a replacement for karyotyping (KT) for products of conception (POC) sample analysis. This is a familiar type of genomic interrogation, which seeks to find the inherited cause of recurrent loss of pregnancy.
Spotting chromosomal abnormalities can potentially offer genetic diagnosis that can establish the reason for miscarriage and or recurrent risk. In fact, a common reason of early pregnancy loss is due to chromosomal abnormality – at least 5% of women attempting to get pregnant encounter repeated loss of 2 or more…
