2025 Men’s March Madness odds: Best bets for Duke-Arizona, Houston-Purdue

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And then there were 16.

The first two rounds of the men’s NCAA Tournament are in the books, and outside a few exciting upsets — like McNeese over Clemson, Drake over Missouri and Arkansas over St. John’s — it’s been mostly chalk city.

That probably won’t change this Thursday and Friday.

My first-round bets finished 4-3 last week, and I’m betting three more games in the coming days. Remember, this space isn’t the place for a million picks or five-leg parlays. These will always be the games I love the most.

Let’s go to work.

Duke (-9, O/U 153.5) vs. Arizona

Be careful with these upper-echelon teams catching big numbers. Could Caleb Love and Arizona shoot their way to a cover? Sure, but bookmakers are clearly more than fine offering all those points. I’ve said…

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